Transcription-independent phosphorylation of the RNA polymerase II C-terminal domain (CTD) involves ERK kinases (MEK1/2).

The largest subunit of the mammalian RNA polymerase II possesses a C-terminal domain (CTD) consisting of 52 repeats of the consensus sequence, Tyr(1)-Ser(2)-Pro(3)-Thr(4)-Ser(5)-Pro(6)-Ser(7). Phosphorylation of the CTD is known to play a key role in gene expression. We now show that treatments such...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Bonnet, F, Vigneron, M, Bensaude, O, Dubois, M F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1999
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10536148/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.22.4399
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