Evidence for the Contribution of Point Mutations to vlsE Variation and for Apparent Constraints on the Net Accumulation of Sequence Changes in vlsE during Infection with Lyme Disease Spirochetes

In the Lyme disease spirochetes, both the ospE and vlsE gene families have been demonstrated to undergo sequence variation during infection. To further investigate the mechanisms associated with the generation of vls variation, single-nucleotide polymorphism and subsequent DNA sequence analyses were...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Principais autores:	Sung, Shian-Ying, McDowell, John V., Marconi, Richard T.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Genetics and Molecular Biology
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11566983/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.20.5855-5861.2001
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