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Twofold Reduction of Phosphofructokinase Activity in Lactococcus lactis Results in Strong Decreases in Growth Rate and in Glycolytic Flux

Two mutant strains of Lactococcus lactis in which the promoter of the las operon, harboring pfk, pyk, and ldh, were replaced by synthetic promoters were constructed. These las mutants had an approximately twofold decrease in the activity of phosphofructokinase, whereas the activities of pyruvate kin...

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Detalles Bibliográficos
Main Authors: Andersen, Heidi W., Solem, Christian, Hammer, Karin, Jensen, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC99644/
https://ncbi.nlm.nih.gov/pubmed/11344154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.11.3458-3467.2001
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