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Twofold Reduction of Phosphofructokinase Activity in Lactococcus lactis Results in Strong Decreases in Growth Rate and in Glycolytic Flux

Two mutant strains of Lactococcus lactis in which the promoter of the las operon, harboring pfk, pyk, and ldh, were replaced by synthetic promoters were constructed. These las mutants had an approximately twofold decrease in the activity of phosphofructokinase, whereas the activities of pyruvate kin...

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Autori principali: Andersen, Heidi W., Solem, Christian, Hammer, Karin, Jensen, Peter R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC99644/
https://ncbi.nlm.nih.gov/pubmed/11344154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.11.3458-3467.2001
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