Role of Adaptor Complex AP-3 in Targeting Wild-Type and Mutated CD63 to Lysosomes

CD63 is a lysosomal membrane protein that belongs to the tetraspanin family. Its carboxyterminal cytoplasmic tail sequence contains the lysosomal targeting motif GYEVM. Strong, tyrosine-dependent interaction of the wild-type carboxyterminal tail of CD63 with the AP-3 adaptor subunit μ3 was observed...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Rous, Brian A., Reaves, Barbara J., Ihrke, Gudrun, Briggs, John A.G., Gray, Sally R., Stephens, David J., Banting, George, Luzio, J. Paul
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11907283/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.01-08-0409
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