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Cooperation of E2F-p130 and Sp1-pRb Complexes in Repression of the Chinese Hamster dhfr Gene

In mammalian cells reiterated binding sites for Sp1 and two overlapping and inverted E2F sites at the transcription start site regulate the dhfr promoter during the cell growth cycle. Here we have examined the contributions of the dhfr Sp1 and E2F sites in the repression of dhfr gene expression. In...

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Bibliografiske detaljer
Main Authors: Chang, Young-Chae, Illenye, Sharon, Heintz, Nicholas H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC99566/
https://ncbi.nlm.nih.gov/pubmed/11158299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.4.1121-1131.2001
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