The Chinese Hamster Dihydrofolate Reductase Replication Origin Beta Is Active at Multiple Ectopic Chromosomal Locations and Requires Specific DNA Sequence Elements for Activity

To identify cis-acting genetic elements essential for mammalian chromosomal DNA replication, a 5.8-kb fragment from the Chinese hamster dihydrofolate reductase (DHFR) locus containing the origin beta (ori-β) initiation region was stably transfected into random ectopic chromosomal locations in a hams...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Altman, Amy L., Fanning, Ellen
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2001
Предметы:	DNA Dynamics and Chromosome Structure
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.4.1098-1110.2001
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