Synergistic Effects of Alpha-Toxin and Perfringolysin O in Clostridium perfringens-Mediated Gas Gangrene

To examine the synergistic effects of alpha-toxin and perfringolysin O in clostridial myonecrosis, homologous recombination was used to construct an alpha-toxin deficient derivative of a perfringolysin O mutant of Clostridium perfringens. The subsequent strain was complemented with separate plasmids...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Awad, Milena M., Ellemor, Darren M., Boyd, Richard L., Emmins, John J., Rood, Julian I.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Molecular Pathogenesis
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98889/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11705975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.12.7904-7910.2001
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