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Synergistic Effects of Alpha-Toxin and Perfringolysin O in Clostridium perfringens-Mediated Gas Gangrene

To examine the synergistic effects of alpha-toxin and perfringolysin O in clostridial myonecrosis, homologous recombination was used to construct an alpha-toxin deficient derivative of a perfringolysin O mutant of Clostridium perfringens. The subsequent strain was complemented with separate plasmids...

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Publicado en:Infect Immun
Autores principales: Awad, Milena M., Ellemor, Darren M., Boyd, Richard L., Emmins, John J., Rood, Julian I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98889/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11705975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.12.7904-7910.2001
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