Synergistic Effects of Alpha-Toxin and Perfringolysin O in Clostridium perfringens-Mediated Gas Gangrene

To examine the synergistic effects of alpha-toxin and perfringolysin O in clostridial myonecrosis, homologous recombination was used to construct an alpha-toxin deficient derivative of a perfringolysin O mutant of Clostridium perfringens. The subsequent strain was complemented with separate plasmids...

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Bibliografiske detaljer
Main Authors: Awad, Milena M., Ellemor, Darren M., Boyd, Richard L., Emmins, John J., Rood, Julian I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98889/
https://ncbi.nlm.nih.gov/pubmed/11705975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7904-7910.2001
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