Host Response to Infection: the Role of CpG DNA in Induction of Cyclooxygenase 2 and Nitric Oxide Synthase 2 in Murine Macrophages

Depending on sequence, bacterial and synthetic DNAs can activate the host immune system and influence the host response to infection. The purpose of this study was to determine the abilities of various phosphorothioate oligonucleotides with cytosine-guanosine-containing motifs (CpG DNA) to activate...

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Pubblicato in:	Infect Immun
Autori principali:	Ghosh, Dipak K., Misukonis, Mary A., Reich, Charles, Pisetsky, David S., Weinberg, J. Brice
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Host Response and Inflammation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11705951/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.12.7703-7710.2001
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