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Role for Inducible Nitric Oxide Synthase in Protection from Chronic Chlamydia trachomatis Urogenital Disease in Mice and Its Regulation by Oxygen Free Radicals

It has been previously reported that although inducible nitric oxide synthase (iNOS) gene knockout (NOS2(−/−)) mice resolve Chlamydia trachomatis genital infection, the production of reactive nitrogen species (RNS) via iNOS protects a significant proportion of mice from hydrosalpinx formation and in...

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Bibliografiske detaljer
Main Authors: Ramsey, K. H., Sigar, I. M., Rana, S. V., Gupta, J., Holland, S. M., Byrne, G. I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98824/
https://ncbi.nlm.nih.gov/pubmed/11705910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7374-7379.2001
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