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Role for Inducible Nitric Oxide Synthase in Protection from Chronic Chlamydia trachomatis Urogenital Disease in Mice and Its Regulation by Oxygen Free Radicals

It has been previously reported that although inducible nitric oxide synthase (iNOS) gene knockout (NOS2(−/−)) mice resolve Chlamydia trachomatis genital infection, the production of reactive nitrogen species (RNS) via iNOS protects a significant proportion of mice from hydrosalpinx formation and in...

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Autors principals: Ramsey, K. H., Sigar, I. M., Rana, S. V., Gupta, J., Holland, S. M., Byrne, G. I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98824/
https://ncbi.nlm.nih.gov/pubmed/11705910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7374-7379.2001
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