DNA Immunization with Trypanosoma cruzi HSP70 Fused to the KMP11 Protein Elicits a Cytotoxic and Humoral Immune Response against the Antigen and Leads to Protection
Murine immunization with Trypanosoma cruzi KMP11-HSP70 fused genes but not the KMP11 gene alone elicited both an immunoglobulin G2a long-lasting humoral immune response against KMP11 protein and activation of CD8(+) cytotoxic T lymphocytes specific for two KMP11 peptides containing A2 motifs. Moreov...
Zapisane w:
| Wydane w: | Infect Immun |
|---|---|
| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
2001
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.10.6558-6563.2001 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|