Both Th1 and Th2 Cytokines Affect the Ability of Monoclonal Antibodies To Protect Mice against Cryptococcus neoformans

Variable-region-identical mouse immunoglobulin G1 (IgG1), IgG2b, and IgG2a monoclonal antibodies to the capsular polysaccharide of Cryptococcus neoformans prolong the lives of mice infected with this fungus, while IgG3 is either not protective or enhances infection. CD4(+) T cells are required for I...

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Autores principales: Beenhouwer, David O., Shapiro, Scott, Feldmesser, Marta, Casadevall, Arturo, Scharff, Matthew D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC98780/
https://ncbi.nlm.nih.gov/pubmed/11553589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6445-6455.2001
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