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Characterization of Anticapsular Monoclonal Antibodies That Regulate Activation of the Complement System by the Cryptococcus neoformans Capsule

Incubation of the encapsulated yeast Cryptococcus neoformans in human serum leads to alternative pathway-mediated deposition of C3 fragments in the capsule. We examined the ability of monoclonal antibodies (MAbs) specific for different epitopes of the major capsular polysaccharide to alter the kinet...

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Detalhes bibliográficos
Main Authors: Kozel, Thomas R., deJong, Bouke C. H., Grinsell, Matthew M., MacGill, Randall S., Wall, Kevin K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108086/
https://ncbi.nlm.nih.gov/pubmed/9529079
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