Transient Transgenic Expression of Gamma Interferon Promotes Legionella pneumophila Clearance in Immunocompetent Hosts

Gamma interferon (IFN-γ) and T1-phenotype immune responses are important components of host defense against a variety of intracellular pathogens, including Legionella pneumophila. The benefit of intrapulmonary adenovirus-mediated IFN-γ gene therapy was investigated in a nonlethal murine model of exp...

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Bibliografiske detaljer
Main Authors: Deng, Jane C., Tateda, Kazuhiro, Zeng, Xianying, Standiford, Theodore J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98773/
https://ncbi.nlm.nih.gov/pubmed/11553582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6382-6390.2001
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