Transient Transgenic Expression of Gamma Interferon Promotes Legionella pneumophila Clearance in Immunocompetent Hosts

Gamma interferon (IFN-γ) and T1-phenotype immune responses are important components of host defense against a variety of intracellular pathogens, including Legionella pneumophila. The benefit of intrapulmonary adenovirus-mediated IFN-γ gene therapy was investigated in a nonlethal murine model of exp...

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Vydáno v:	Infect Immun
Hlavní autoři:	Deng, Jane C., Tateda, Kazuhiro, Zeng, Xianying, Standiford, Theodore J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2001
Témata:	Microbial Immunity and Vaccines
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.10.6382-6390.2001
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