Macrophage Inflammatory Protein 1α/CCL3 Is Required for Clearance of an Acute Klebsiella pneumoniae Pulmonary Infection

The objective of these studies was to determine the role of macrophage inflammatory protein 1α/CCL3 in pulmonary host defense during Klebsiella pneumoniae infection. Following intratracheal inoculation, 7-day survival of CCL3(−/−) mice was less than 10%, compared to 60% for CCL3(+/+) mice. Survival...

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Autori principali: Lindell, Dennis M., Standiford, Theodore J., Mancuso, Peter, Leshen, Zachary J., Huffnagle, Gary B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98771/
https://ncbi.nlm.nih.gov/pubmed/11553580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6364-6369.2001
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