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Shiga Toxins Induce, Superinduce, and Stabilize a Variety of C-X-C Chemokine mRNAs in Intestinal Epithelial Cells, Resulting in Increased Chemokine Expression

Exposure of humans to Shiga toxins (Stxs) is a risk factor for hemolytic-uremic syndrome (HUS). Because Stx-producing Escherichia coli (STEC) is a noninvasive enteric pathogen, the extent to which Stxs can cross the host intestinal epithelium may affect the risk of developing HUS. We have previously...

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Detalles Bibliográficos
Autores principales: Thorpe, Cheleste M., Smith, Wendy E., Hurley, Bryan P., Acheson, David W. K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC98744/
https://ncbi.nlm.nih.gov/pubmed/11553553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6140-6147.2001
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