Characterization of Haemophilus ducreyi cdtA, cdtB, and cdtC Mutants in In Vitro and In Vivo Systems

Haemophilus ducreyi expresses a soluble cytolethal distending toxin (CDT) that is encoded by the cdtABC gene cluster and can be detected in culture supernatant fluid by its ability to kill HeLa cells. The cdtA, cdtB, and cdtC genes of H. ducreyi were cloned independently into plasmid vectors, and th...

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Autori principali: Lewis, David A., Stevens, Marla K., Latimer, Jo L., Ward, Christine K., Deng, Kaiping, Blick, Robert, Lumbley, Sheryl R., Ison, Catherine A., Hansen, Eric J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98678/
https://ncbi.nlm.nih.gov/pubmed/11500438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5626-5634.2001
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