Purification, Characterization, and Immunogenicity of a Disulfide Cross-Linked Plasmodium vivax Vaccine Candidate Antigen, Merozoite Surface Protein 1, Expressed in Escherichia coli

The Plasmodium vivax merozoite surface protein 1 (MSP-1) 42-kDa fragment (PvMSP-1 p42) is a promising vaccine candidate antigen against the blood stage of the malarial parasite. We have developed a process for the production of this vaccine target, keeping in mind its use in human volunteers. A nove...

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Detalles Bibliográficos
Main Authors: Dutta, Sheetij, Ware, Lisa A., Barbosa, Arnoldo, Ockenhouse, Christian F., Lanar, David E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98658/
https://ncbi.nlm.nih.gov/pubmed/11500418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5464-5470.2001
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