Purification, Characterization, and Immunogenicity of a Disulfide Cross-Linked Plasmodium vivax Vaccine Candidate Antigen, Merozoite Surface Protein 1, Expressed in Escherichia coli

The Plasmodium vivax merozoite surface protein 1 (MSP-1) 42-kDa fragment (PvMSP-1 p42) is a promising vaccine candidate antigen against the blood stage of the malarial parasite. We have developed a process for the production of this vaccine target, keeping in mind its use in human volunteers. A nove...

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Pubblicato in:	Infect Immun
Autori principali:	Dutta, Sheetij, Ware, Lisa A., Barbosa, Arnoldo, Ockenhouse, Christian F., Lanar, David E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.9.5464-5470.2001
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