Cellular and Humoral Immune Responses and Protection against Schistosomes Induced by a Radiation-Attenuated Vaccine in Chimpanzees

The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons. To strengthen its status as a paradigm for a human recombinant antigen vaccine, we have undertaken a small-scale vaccination and challen...

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Detalhes bibliográficos
Main Authors: Eberl, Matthias, Langermans, Jan A. M., Frost, Patrice A., Vervenne, Richard A., van Dam, Govert J., Deelder, André M., Thomas, Alan W., Coulson, Patricia S., Wilson, R. Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98645/
https://ncbi.nlm.nih.gov/pubmed/11500405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5352-5362.2001
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