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Altered Patterns of Gene Expression Underlying the Enhanced Immunogenicity of Radiation-Attenuated Schistosomes

BACKGROUND: Schistosome cercariae only elicit high levels of protective immunity against a challenge infection if they are optimally attenuated by exposure to ionising radiation that truncates their migration in the lungs. However, the underlying molecular mechanisms responsible for the altered phen...

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Detalhes bibliográficos
Main Authors: Dillon, Gary P., Feltwell, Theresa, Skelton, Jason, Coulson, Patricia S., Wilson, R. Alan, Ivens, Alasdair C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375114/
https://ncbi.nlm.nih.gov/pubmed/18493602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000240
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