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Arginine-Specific Protease from Porphyromonas gingivalis Activates Protease-Activated Receptors on Human Oral Epithelial Cells and Induces Interleukin-6 Secretion

Periodontitis is a chronic inflammatory disease affecting oral tissues. Oral epithelial cells represent the primary barrier against bacteria causing the disease. We examined the responses of such cells to an arginine-specific cysteine proteinase (RgpB) produced by a causative agent of periodontal di...

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Autors principals: Lourbakos, Afrodite, Potempa, Jan, Travis, James, D'Andrea, Michael R., Andrade-Gordon, Patricia, Santulli, Rosemary, Mackie, Eleanor J., Pike, Robert N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98608/
https://ncbi.nlm.nih.gov/pubmed/11447194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.5121-5130.2001
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