Induction of Cell-Mediated Immunity against Mycobacterium tuberculosis Using DNA Vaccines Encoding Cytotoxic and Helper T-Cell Epitopes of the 38-Kilodalton Protein

Cell-mediated immune responses are crucial in the protection against tuberculosis. In this study, we constructed DNA vaccines encoding cytotoxic T lymphocytes (CTL) and T helper cell (Th) epitopes of the 38-kDa lipoglycoprotein of Mycobacterium tuberculosis and analyzed and compared their immunogeni...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Fonseca, Dora P. A. J., Benaissa-Trouw, Barry, van Engelen, Marloes, Kraaijeveld, Cees A., Snippe, Harm, Verheul, André F. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98572/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.8.4839-4845.2001
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