Construction, Genotypic and Phenotypic Characterization, and Immunogenicity of Attenuated ΔguaBA Salmonella enterica Serovar Typhi Strain CVD 915

A promising live attenuated typhoid vaccine candidate strain for mucosal immunization was developed by introducing a deletion in the guaBA locus of pathogenic Salmonella enterica serovar Typhi strain Ty2. The resultant ΔguaBA mutant, serovar Typhi CVD 915, has a gene encoding resistance to arsenite...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Wang, Jin Yuang, Pasetti, Marcela F., Noriega, Fernando R., Anderson, Richard J., Wasserman, Steven S., Galen, James E., Sztein, Marcelo B., Levine, Myron M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98559/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.8.4734-4741.2001
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