Endogenous Interleukin-10 Is Required for Prevention of a Hyperinflammatory Intracerebral Immune Response in Listeria monocytogenes Meningoencephalitis

To analyze the role of interleukin-10 (IL-10) in bacterial cerebral infections, we studied cerebral listeriosis in IL-10-deficient (IL-10(−/−)) and wild-type (WT) mice, the latter of which express high levels of IL-10 in both primary and secondary cerebral listeriosis. IL-10(−/−) mice succumbed to p...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Deckert, Martina, Soltek, Sabine, Geginat, Gernot, Lütjen, Sonja, Montesinos-Rongen, Manuel, Hof, Herbert, Schlüter, Dirk
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2001
Subjects:	Host Response and Inflammation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98533/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11402000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.7.4561-4571.2001
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