Endogenous Interleukin-10 Is Required for Prevention of a Hyperinflammatory Intracerebral Immune Response in Listeria monocytogenes Meningoencephalitis

To analyze the role of interleukin-10 (IL-10) in bacterial cerebral infections, we studied cerebral listeriosis in IL-10-deficient (IL-10(−/−)) and wild-type (WT) mice, the latter of which express high levels of IL-10 in both primary and secondary cerebral listeriosis. IL-10(−/−) mice succumbed to p...

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Detalhes bibliográficos
Main Authors: Deckert, Martina, Soltek, Sabine, Geginat, Gernot, Lütjen, Sonja, Montesinos-Rongen, Manuel, Hof, Herbert, Schlüter, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98533/
https://ncbi.nlm.nih.gov/pubmed/11402000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4561-4571.2001
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