Protection against Anthrax Lethal Toxin Challenge by Genetic Immunization with a Plasmid Encoding the Lethal Factor Protein

The ability of genetic vaccination to protect against a lethal challenge of anthrax toxin was evaluated. BALB/c mice were immunized via gene gun inoculation with eucaryotic expression vector plasmids encoding either a fragment of the protective antigen (PA) or a fragment of lethal factor (LF). Plasm...

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Bibliografiske detaljer
Main Authors:	Price, Brian M., Liner, Adriane L., Park, Sukjoon, Leppla, Stephen H., Mateczun, Alfred, Galloway, Darrell R.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology 2001
Fag:	Microbial Immunity and Vaccines
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC98526/ https://ncbi.nlm.nih.gov/pubmed/11401993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4509-4515.2001
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Protection against Anthrax Lethal Toxin Challenge by Genetic Immunization with a Plasmid Encoding the Lethal Factor Protein

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