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Deletion of wboA Enhances Activation of the Lectin Pathway of Complement in Brucella abortus and Brucella melitensis

Brucella spp. are gram-negative intracellular pathogens that survive and multiply within phagocytic cells of their hosts. Smooth organisms present O polysaccharides (OPS) on their surface. These OPS help the bacteria avoid the bactericidal action of serum. The wboA gene, coding for the enzyme glycos...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Fernandez-Prada, Carmen M., Nikolich, Mikeljon, Vemulapalli, Ramesh, Sriranganathan, Nammalwar, Boyle, Stephen M., Schurig, Gerhardt G., Hadfield, Ted L., Hoover, David L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98513/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11401980/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.7.4407-4416.2001
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