Helicobacter hepaticus-Induced Colitis in Interleukin-10-Deficient Mice: Cytokine Requirements for the Induction and Maintenance of Intestinal Inflammation

We have previously shown that specific-pathogen-free interleukin-10 (IL-10)-deficient (IL-10 KO) mice reconstituted with Helicobacter hepaticus develop severe colitis associated with a Th1-type cytokine response. In the present study, we formally demonstrate that IL-12 is crucial for disease inducti...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Kullberg, Marika C., Rothfuchs, Antonio Gigliotti, Jankovic, Dragana, Caspar, Patricia, Wynn, Thomas A., Gorelick, Peter L., Cheever, Allen W., Sher, Alan
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2001
Matèries:	Host Response and Inflammation
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98456/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11401959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.7.4232-4241.2001
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