Increased Immunogenicity and Induction of Class Switching by Conjugation of Complement C3d to Pneumococcal Serotype 14 Capsular Polysaccharide

Previous studies have demonstrated an adjuvant effect for the C3d fragment of complement C3 when coupled to T-dependent protein antigens. In this study, we examined the antibody response to covalent conjugates of C3d and a T-independent antigen, the capsular polysaccharide of serotype 14 Streptococc...

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Hlavní autoři: Test, Samuel T., Mitsuyoshi, Joyce, Connolly, Charles C., Lucas, Alexander H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC98257/
https://ncbi.nlm.nih.gov/pubmed/11292721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3031-3040.2001
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