Increased Immunogenicity and Induction of Class Switching by Conjugation of Complement C3d to Pneumococcal Serotype 14 Capsular Polysaccharide

Previous studies have demonstrated an adjuvant effect for the C3d fragment of complement C3 when coupled to T-dependent protein antigens. In this study, we examined the antibody response to covalent conjugates of C3d and a T-independent antigen, the capsular polysaccharide of serotype 14 Streptococc...

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Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Test, Samuel T., Mitsuyoshi, Joyce, Connolly, Charles C., Lucas, Alexander H.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Microbial Immunity and Vaccines
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98257/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.3031-3040.2001
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