Interleukin-4 Is Essential for the Control of Microfilariae in Murine Infection with the Filaria Litomosoides sigmodontis

Litomosoides sigmodontis is the only filaria which develops from infective larvae into microfilaria-producing adults in immunocompetent laboratory mice. In this study we report that interleukin-4 knockout (IL-4 KO) mice have an up to 100-fold-higher and a significantly prolonged microfilaremia compa...

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Detalhes bibliográficos
Main Authors: Volkmann, Lars, Saeftel, Michael, Bain, Odile, Fischer, Kerstin, Fleischer, Bernhard, Hoerauf, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98247/
https://ncbi.nlm.nih.gov/pubmed/11292711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.2950-2956.2001
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