Interleukin-10 Stimulates Coxiella burnetii Replication in Human Monocytes through Tumor Necrosis Factor Down-Modulation: Role in Microbicidal Defect of Q Fever

Coxiella burnetii, an obligate intracellular bacterium, is the agent of Q fever. The chronic form of the disease is associated with the overproduction of interleukin-10 and deficient C. burnetii killing by monocytes. We hypothesized that the replication of C. burnetii inside monocytes requires a mac...

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Autors principals: Ghigo, Eric, Capo, Christian, Raoult, Didier, Mege, Jean-Louis
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98164/
https://ncbi.nlm.nih.gov/pubmed/11254592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2345-2352.2001
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