Interleukin-10 Stimulates Coxiella burnetii Replication in Human Monocytes through Tumor Necrosis Factor Down-Modulation: Role in Microbicidal Defect of Q Fever

Coxiella burnetii, an obligate intracellular bacterium, is the agent of Q fever. The chronic form of the disease is associated with the overproduction of interleukin-10 and deficient C. burnetii killing by monocytes. We hypothesized that the replication of C. burnetii inside monocytes requires a mac...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Ghigo, Eric, Capo, Christian, Raoult, Didier, Mege, Jean-Louis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98164/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11254592/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.4.2345-2352.2001
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