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Essential Role for Cellular Phosphoglucomutase in Virulence of Type 3 Streptococcus pneumoniae

Synthesis of the Streptococcus pneumoniae type 3 capsule requires the pathway glucose-6-phosphate (Glc-6-P) → Glc-1-P → UDP-Glc → UDP-glucuronic acid (UDP-GlcUA) → (GlcUA-Glc)(n). The UDP-Glc dehydrogenase and synthase necessary for the latter two steps, and essential for capsule production, are enc...

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Podrobná bibliografie
Hlavní autoři:	Hardy, Gail G., Magee, Ashalla D., Ventura, Christy L., Caimano, Melissa J., Yother, Janet
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2001
Témata:	Molecular Pathogenesis
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC98160/ https://ncbi.nlm.nih.gov/pubmed/11254588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2309-2317.2001
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Essential Role for Cellular Phosphoglucomutase in Virulence of Type 3 Streptococcus pneumoniae

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