Streptococcus iniae Phosphoglucomutase Is a Virulence Factor and a Target for Vaccine Development

Streptococcus iniae represents a major health and economic problem in fish species worldwide. Random Tn917 mutagenesis and high-throughput screening in a hybrid striped bass (HSB) model of meningoencephalitis identified attenuated S. iniae mutants. The Tn917 insertion in one mutant disrupted an S. i...

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Bibliographic Details
Main Authors: Buchanan, John T., Stannard, Jason A., Lauth, Xavier, Ostland, Vaughn E., Powell, Henry C., Westerman, Mark E., Nizet, Victor
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230984/
https://ncbi.nlm.nih.gov/pubmed/16177373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6935-6944.2005
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