Antibody against Surface-Bound C5a Peptidase Is Opsonic and Initiates Macrophage Killing of Group B Streptococci

The capsular polysaccharides of group B streptococci (GBS) are a primary focus of vaccine development. Immunogenicity and long-lasting protection are best achieved by conjugating polysaccharides to a T-cell-dependent protein antigen. Streptococcal C5a peptidase (SCPB) is a conserved surface protein...

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Detalhes bibliográficos
Main Authors: Cheng, Qi, Carlson, Brian, Pillai, Sub, Eby, Ron, Edwards, Lorri, Olmsted, Stephen B., Cleary, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98159/
https://ncbi.nlm.nih.gov/pubmed/11254587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2302-2308.2001
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