Antibody against Surface-Bound C5a Peptidase Is Opsonic and Initiates Macrophage Killing of Group B Streptococci

The capsular polysaccharides of group B streptococci (GBS) are a primary focus of vaccine development. Immunogenicity and long-lasting protection are best achieved by conjugating polysaccharides to a T-cell-dependent protein antigen. Streptococcal C5a peptidase (SCPB) is a conserved surface protein...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Cheng, Qi, Carlson, Brian, Pillai, Sub, Eby, Ron, Edwards, Lorri, Olmsted, Stephen B., Cleary, Patrick
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2001
Subjects:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98159/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11254587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.4.2302-2308.2001
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