Human Monoclonal Antibodies against Pseudomonas aeruginosa Lipopolysaccharide Derived from Transgenic Mice Containing Megabase Human Immunoglobulin Loci Are Opsonic and Protective against Fatal Pseudomonas Sepsis

Pseudomonas aeruginosa is a significant human pathogen, and no vaccine is commercially available. Passive antibody prophylaxis using monoclonal antibodies (MAb) against protective P. aeruginosa epitopes is an alternative strategy for preventing P. aeruginosa infection, but mouse MAb are not suitable...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Hemachandra, Sonali, Kamboj, Kulwant, Copfer, Janna, Pier, Gerald, Green, Larry L., Schreiber, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98149/
https://ncbi.nlm.nih.gov/pubmed/11254577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2223-2229.2001
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi