Critical Role of CD14 for Production of Proinflammatory Cytokines and Cytokine Inhibitors during Sepsis with Failure To Alter Morbidity or Mortality

We investigated the immunopathophysiologic responses during sepsis induced by cecal ligation and puncture (CLP) in CD4-deficient (CD14 knockout [CD14KO]) mice. Our studies were designed to specifically test the role of CD14 in the inflammatory response to sepsis and to ascertain if alterations would...

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Detalhes bibliográficos
Main Authors: Ebong, Samuel J., Goyert, Sanna M., Nemzek, Jean A., Kim, Jiyoun, Bolgos, Gerald L., Remick, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98135/
https://ncbi.nlm.nih.gov/pubmed/11254563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2099-2106.2001
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