Critical Role of CD14 for Production of Proinflammatory Cytokines and Cytokine Inhibitors during Sepsis with Failure To Alter Morbidity or Mortality

We investigated the immunopathophysiologic responses during sepsis induced by cecal ligation and puncture (CLP) in CD4-deficient (CD14 knockout [CD14KO]) mice. Our studies were designed to specifically test the role of CD14 in the inflammatory response to sepsis and to ascertain if alterations would...

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Bibliografiske detaljer
Main Authors: Ebong, Samuel J., Goyert, Sanna M., Nemzek, Jean A., Kim, Jiyoun, Bolgos, Gerald L., Remick, Daniel G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98135/
https://ncbi.nlm.nih.gov/pubmed/11254563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2099-2106.2001
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