Molecular Cloning and Characterization of WdPKS1, a Gene Involved in Dihydroxynaphthalene Melanin Biosynthesis and Virulence in Wangiella (Exophiala) dermatitidis

1,8-Dihydroxynaphthalene (1,8-DHN) is a fungal polyketide that contributes to virulence when polymerized to 1,8-DHN melanin in the cell walls of Wangiella dermatitidis, an agent of phaeohyphomycosis in humans. To begin a genetic analysis of the initial synthetic steps leading to 1,8-DHN melanin bios...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Feng, Bin, Wang, Xu, Hauser, Melinda, Kaufmann, Sarah, Jentsch, Simone, Haase, Gerhard, Becker, Jeffery M., Szaniszlo, Paul J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Fungal and Parasitic Infections
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98085/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179356/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.3.1781-1794.2001
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