Molecular Cloning and Characterization of WdPKS1, a Gene Involved in Dihydroxynaphthalene Melanin Biosynthesis and Virulence in Wangiella (Exophiala) dermatitidis

1,8-Dihydroxynaphthalene (1,8-DHN) is a fungal polyketide that contributes to virulence when polymerized to 1,8-DHN melanin in the cell walls of Wangiella dermatitidis, an agent of phaeohyphomycosis in humans. To begin a genetic analysis of the initial synthetic steps leading to 1,8-DHN melanin bios...

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Bibliographische Detailangaben
Hauptverfasser: Feng, Bin, Wang, Xu, Hauser, Melinda, Kaufmann, Sarah, Jentsch, Simone, Haase, Gerhard, Becker, Jeffery M., Szaniszlo, Paul J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98085/
https://ncbi.nlm.nih.gov/pubmed/11179356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1781-1794.2001
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