Use of a Whole Genome Approach To Identify Vaccine Molecules Affording Protection against Streptococcus pneumoniae Infection

Microbial targets for protective humoral immunity are typically surface-localized proteins and contain common sequence motifs related to their secretion or surface binding. Exploiting the whole genome sequence of the human bacterial pathogen Streptococcus pneumoniae, we identified 130 open reading f...

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Main Authors: Wizemann, Theresa M., Heinrichs, Jon H., Adamou, John E., Erwin, Alice L., Kunsch, Charles, Choi, Gil H., Barash, Steven C., Rosen, Craig A., Masure, H. Robert, Tuomanen, Elaine, Gayle, Anthony, Brewah, Yambasu A., Walsh, William, Barren, Philip, Lathigra, Raju, Hanson, Mark, Langermann, Solomon, Johnson, Syd, Koenig, Scott
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98061/
https://ncbi.nlm.nih.gov/pubmed/11179332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1593-1598.2001
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