Clostridium difficile Toxins Disrupt Epithelial Barrier Function by Altering Membrane Microdomain Localization of Tight Junction Proteins

The anaerobic bacterium Clostridium difficile is the etiologic agent of pseudomembranous colitis. C. difficile toxins TcdA and TcdB are UDP-glucosyltransferases that monoglucosylate and thereby inactivate the Rho family of GTPases (W. P. Ciesla, Jr., and D. A. Bobak, J. Biol. Chem. 273:16021–16026,...

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Detaylı Bibliyografya

Yayımlandı:	Infect Immun
Asıl Yazarlar:	Nusrat, A., von Eichel-Streiber, C., Turner, J. R., Verkade, P., Madara, J. L., Parkos, C. A.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 2001
Konular:	Molecular Pathogenesis
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98024/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.3.1329-1336.2001
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