Restoration of Mga Function to a Streptococcus pyogenes Strain (M Type 50) That Is Virulent in Mice

The Mga protein in B514Sm, a Streptococcus pyogenes strain isolated as a mouse pathogen, contains amino acid substitutions at conserved sites that render the protein defective. Replacement of mga50 with the functional homolog mga4.1 restored full expression of Mga-regulated proteins. Restoration of...

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Detalhes bibliográficos
Main Authors: Limbago, Brandi, McIver, Kevin S., Penumalli, Vikram, Weinrick, Brian, Scott, June R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98010/
https://ncbi.nlm.nih.gov/pubmed/11160026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.1215-1220.2001
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