Restoration of Mga Function to a Streptococcus pyogenes Strain (M Type 50) That Is Virulent in Mice

The Mga protein in B514Sm, a Streptococcus pyogenes strain isolated as a mouse pathogen, contains amino acid substitutions at conserved sites that render the protein defective. Replacement of mga50 with the functional homolog mga4.1 restored full expression of Mga-regulated proteins. Restoration of...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Limbago, Brandi, McIver, Kevin S., Penumalli, Vikram, Weinrick, Brian, Scott, June R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Molecular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98010/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160026/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.2.1215-1220.2001
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