Reduced Virulence of Group A Streptococcal Tn916 Mutants That Do Not Produce Streptolysin S

Streptolysin S (SLS) is a potent cytolytic toxin produced by nearly all group A streptococci (GAS). SLS-deficient Tn916 insertional mutants were generated from two clinical isolates of GAS, MGAS166s and T18Ps (M serotypes 1 and 18, respectively), by transposon mutagenesis using Tn916 donor strain En...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Betschel, Stephen D., Borgia, Sergio M., Barg, Neil L., Low, Donald E., De Azavedo, Joyce C. S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9529097/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.4.1671-1679.1998
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