Reduced Virulence of Group A Streptococcal Tn916 Mutants That Do Not Produce Streptolysin S

Streptolysin S (SLS) is a potent cytolytic toxin produced by nearly all group A streptococci (GAS). SLS-deficient Tn916 insertional mutants were generated from two clinical isolates of GAS, MGAS166s and T18Ps (M serotypes 1 and 18, respectively), by transposon mutagenesis using Tn916 donor strain En...

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Bibliografski detalji
Glavni autori: Betschel, Stephen D., Borgia, Sergio M., Barg, Neil L., Low, Donald E., De Azavedo, Joyce C. S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Molecular and Cellular Pathogenesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC108104/
https://ncbi.nlm.nih.gov/pubmed/9529097
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