DNA Immunization by Plasmodium falciparum Liver-Stage Antigen 3 Induces Protection against Plasmodium yoelii Sporozoite Challenge

DNA-based immunization of mice by Plasmodium falciparum liver-stage antigen 3 (PfLSA3), a novel highly conserved P. falciparum preerythrocytic antigen, was evaluated. Animals developed a dominant Th1 immune response (high gamma interferon T-cell responses and predominance of immunoglobulin G2a) to e...

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Pubblicato in:	Infect Immun
Autori principali:	Sauzet, Jean-Pierre, Perlaza, Blanca-Liliana, Brahimi, Karima, Daubersies, Pierre, Druilhe, Pierre
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.2.1202-1206.2001
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